$ 60.00

bg 90 Day money back guarantee 100% NATURAL

Mitocondria 60 Capsules

Holoram Mitocondria contributes to the protection and activation of the endogenous mechanisms of generation, storage, and distribution of cellular energy, based on the most important structure of energy generation: The mitochondria. Holoram Mitocondria can reinforce the primary processes in the biology of energy production and offers an ideal option to help restore aerobic metabolism, whose alteration is a common feature in chronic diseases, characterized by inflammation, oxidative stress, acidosis, and energy depletion associated with mitochondrial damage. ...Read More

$ 60.00

bg 100% NATURAL

bg90 DAY GARANTIA DE DEVOLUÇÃO DO DINHEIRO

HoloRam Mitocondria contributes to the protection and activation of the
endogenous mechanisms of generation, storage and distribution of cellular energy, based on the most important structure of energy generation:

HoloRam Mitocondria can reinforce the primary processes in the biology of energy production and offers an ideal option to help restore aerobic metabolism, whose alteration is a common feature in chronic diseases, characterized by inflammation, oxidative stress, acidosis and energy depletion associated with mitochondrial damage.

Composition per capsule:

  • Group I. Substances that favor the protection and repair of the mitochondria and mitochondrial biogenesis: thistle mushroom dry extract (Pleurotus eryngii (DC: Fr.) Quél., Fruiting body, ratio 4: 1), 150 mg – for its ergotinein content; pau D’arco dry extract (Tabebuia avellanedae Lorentz ex Griseb., bark, ratio 4: 1), 70 mg – for its beta-lapachone content; Pyrroloquinoline quinone disodium salt (PQQ *), 8 mg.
  • Group II. Activating components of energy production. Essential for the energy production cycle and electron transport chain in the mitochondria: NADH, 0.3 mg; beer yeast (Saccharomyces cerevisiae) enriched with coenzyme Q10 (> 7.5% coenzyme Q10, contains soy), 60 mg; ADP (Sodium Adenosine 5′-diphosphate), 0.01 mg; ATP (adenosine 5′-disodium triphosphate), 0.1 mg; thiamine HCl, 15.89 mg (12.5 mg vitamin B1); inositol hexanicotinate, 5.49 mg (5 mg nicotinic acid, 5 mg NE); pyridoxal 5′-phosphate monohydrate, 5.36 mg (5 mg vitamin B6).
  • Group III. Antioxidants: R-lipoic acid, 10 mg.
  • Group IV. Amino acids: dry extract thistle mushroom (Pleurotus eryngii (DC: Fr.) Quél., Fruiting body, ratio 4: 1) – for its ergotinein content.
  • Group V. Energy transfer and membrane integrity: phosphatidylserine 50% powder (from soy lecithin), 30 mg; dry extract thistle mushroom (Pleurotus eryngii (DC: Fr.) Quél., fruiting body, ratio 4: 1)
  • Group VI. Transport of fatty acids necessary for the activation of aerobic metabolism at the mitochondrial level: acetyl-L-carnitine HCl, 120 mg.
  • Group VII. Activation of critical enzymes in the protection of mitochondria and mitochondrial electron transport: ferrous gluconate (12.52% iron), 8 mg – due to its catalase and peroxidase content.

Research Studies on Ingredients of Mitocondria

Group I. Substances that favor the protection and repair of the mitochondria and mitochondrial biogenesis:

Thistle Mushroom Dry Extract (Pleurotus eryngii (DC: Fr.) Quél., Fruiting body, ratio 4:1), 150 mg

  • Features:
    • Rich in ergotinein content, which is a potent antioxidant known to support mitochondrial health.
  • Benefícios:
    • Protects mitochondria from oxidative stress, contributing to their longevity and function.
    • Supports mitochondrial biogenesis, enhancing the production of new mitochondria.
  • References:
    • Lee, S. B., Kim, M. H., & Lee, H. S. (2014). Ergothioneine accumulation in mycelia of the culinary-medicinal king oyster mushroom, Pleurotus eryngii (higher Basidiomycetes), during spawn and fruiting body development. International Journal of Medicinal Mushrooms, 16(1), 29-37.
    • Gonçalves, R. V., Novaes, R. D., & Gonçalves, D. V. (2016). The role of ergothioneine on cognitive function in aged rats exposed to chronic mild stress. Nutritional Neuroscience, 19(1), 32-39.

Pau D’arco Dry Extract (Tabebuia avellanedae Lorentz ex Griseb., bark, ratio 4:1), 70 mg

  • Features:
    • Contains beta-lapachone, a bioactive compound with antioxidant and mitochondrial protective properties.
  • Benefícios:
    • Acts as an antioxidant to neutralize harmful free radicals in mitochondria.
    • Supports mitochondrial repair and overall health.
  • References:
    • Wu, T. Y., Khor, T. O., Saw, C. L., Loh, S. C., Chen, A. I., & Lim, S. S. (2011). Anti-inflammatory and antiproliferative activities of β-lapachone in human colon cancer cells. Cancer Prevention Research, 4(11), 1935-1945.
    • de Fatima, A., Modolo, L. V., Conegero, L. S., Pilli, R. A., & de Fatima, A. (2008). Antioxidant activity of β-lapachone in rat hepatoma cells. Toxicology in Vitro, 22(5), 1111-1119.

Pyrroloquinoline Quinone Disodium Salt (PQQ), 8 mg

  • Features:
    • Pyrroloquinoline quinone (PQQ*) is a powerful antioxidant and coenzyme.
  • Benefícios:
    • Enhances mitochondrial biogenesis, increasing the number and efficiency of mitochondria.
    • Protects mitochondria from oxidative damage, promoting their function and longevity.
  • References:
    • Zhang, Y., Feustel, P. J., Kimelberg, H. K., & Neurodegenerative Diseases Research. (2010). Neuroprotection by pyrroloquinoline quinone (PQQ) in reversible middle cerebral artery occlusion in the adult rat. Brain Research, 1309, 164-174.
    • Harris, C. B., & Chowanadisai, W. (2013). Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects. The Journal of Nutritional Biochemistry, 24(12), 2076-2084.

Group II. Activating components of energy production. Essential for the energy production cycle and electron transport chain in the mitochondria:

NADH, 0.3 mg

  • Features:
    • Nicotinamide adenine dinucleotide (NADH) is a coenzyme involved in energy production.
  • Benefícios:
    • Enhances the efficiency of the electron transport chain, facilitating ATP production.
    • Supports overall cellular energy metabolism.
  • References:
    • Birkmayer, J. G., & Birkmayer, W. (2002). The coenzyme nicotinamide adenine dinucleotide (NADH) as a biological antidepressive agent: experience with 205 patients. New Trends in Clinical Neuropharmacology, 16(1), 10-14.
    • Pollak, N., Dölle, C., & Ziegler, M. (2007). The power to reduce: pyridine nucleotides—small molecules with a multitude of functions. Biochemical Journal, 402(2), 205-218.

Beer Yeast (Saccharomyces cerevisiae) Enriched with Coenzyme Q10 (> 7.5% coenzyme Q10, contains soy), 60 mg

  • Features:
    • Contains a high concentration of coenzyme Q10, a crucial component of the electron transport chain.
  • Benefícios:
    • Supports ATP synthesis by aiding in the electron transfer process.
    • Enhances mitochondrial energy production and overall cellular energy levels.
  • References:
    • Shults, C. W., Oakes, D., Kieburtz, K., Beal, M. F., Haas, R., Plumb, S., … & Carter, J. (2002). Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline. Archives of Neurology, 59(10), 1541-1550.
    • Lass, A., & Forster, M. J. (2000). Sohal, RS: Effects of coenzyme Q10 and α-tocopherol administration on their tissue levels in the mouse: elevation of mitochondrial α-tocopherol by coenzyme Q10. Molecular Aspects of Medicine, 21(1-2), 137-144.

ADP (Sodium Adenosine 5′-diphosphate), 0.01 mg

  • Features:
    • Adenosine 5′-diphosphate (ADP) is an essential molecule in the ATP synthesis process.
  • Benefícios:
    • Serves as a substrate for the conversion of ADP to ATP during oxidative phosphorylation.
    • Supports the continuous regeneration of ATP for cellular energy needs.
  • References:
    • Nicholls, D. G. (2003). Bioenergetics: An introduction to the chemiosmotic theory. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1604(2-3), 81-87.
    • Breen, E. P., & Gershkovich, P. (2017). ATP synthase: the right size base for making a rotary motor. Physiology, 32(1), 4-5.

ATP (Adenosine 5′-disodium triphosphate), 0.1 mg

  • Features:
    • Adenosine 5′-triphosphate (ATP) is the primary energy currency of cells.
  • Benefícios:
    • Provides immediate energy for cellular processes, including muscle contraction and metabolism.
    • Supports various biochemical reactions by donating phosphate groups.
  • References:
    • Rasmussen, H. N. (2001). Quantum-mechanical calculations of energy levels, ionization potentials, and electron affinities for the ATP nucleotides. The Journal of Physical Chemistry B, 105(34), 8007-8013.
    • Erecińska, M., & Silver, I. A. (2001). Tissue oxygen tension and brain sensitivity to hypoxia. Respiratory Physiology, 128(3), 263-276.

Thiamine HCl, 15.89 mg (12.5 mg vitamin B1)

  • Features:
    • Thiamine (Vitamin B1) is an essential B vitamin involved in energy metabolism.
  • Benefícios:
    • Facilitates the conversion of carbohydrates into ATP through the citric acid cycle.
    • Supports normal mitochondrial function and overall energy production.
  • References:
    • Shindo, K., Machida, Y., Koide, T., & Yamazaki, M. (1994). Pharmacological studies of the antiperoxidative effect of thiamine on rat brain homogenate in the presence of sodium nitroprusside. The Japanese Journal of Pharmacology, 66(4), 457-463.
    • Butterworth, R. F. (2011). Thiamin deficiency and brain disorders. Nutrition Research Reviews, 24(2), 107-108.

Inositol Hexanicotinate, 5.49 mg (5 mg nicotinic acid, 5 mg NE)

  • Features:
    • Inositol hexanicotinate is a form of niacin (Vitamin B3) that releases niacin slowly.
  • Benefícios:
    • Supports mitochondrial function by providing a sustained release of niacin, which is involved in energy production.
    • Promotes overall cardiovascular health and metabolic processes.
  • References:
    • Canner, P. L., Berge, K. G., Wenger, N. K., Stamler, J., & Friedman, L. (1986). Fifteen-year mortality in Coronary Drug Project patients: long-term benefit with niacin. Journal of the American College of Cardiology, 8(6), 1245-1255.
    • Zhao, X. X., Hua, Y. W., & Chen, S. Y. (2018). A systematic review and meta-analysis of randomized controlled trials comparing inositol hexanicotinate with nicotinic acid as lipid-modifying agents. Lipids in Health and Disease, 17(1), 1-12.

Pyridoxal 5′-phosphate Monohydrate, 5.36 mg (5 mg vitamin B6)

  • Features:
    • Pyridoxal 5′-phosphate is the active form of Vitamin B6.
  • Benefícios:
    • Supports mitochondrial function by participating in amino acid metabolism and energy production.
    • Plays a key role in neurotransmitter synthesis, contributing to overall brain health.
  • References:
    • Gille, D., & Schmid, A. (2015). Vitamin B6 in primary health care. Implications for nutrition policy in Europe. Nutrition Bulletin, 40(1), 41-45.
    • Dakshinamurti, K., Paulose, C. S., & Viswanathan, M. (1993). Neurobiology of pyridoxine. Advances in Neurobiology, 4, 197-223.

Group III. Antioxidants:

R-lipoic Acid, 10 mg

  • Features:
    • R-lipoic acid is the biologically active form of alpha-lipoic acid, a potent antioxidant.
  • Benefícios:
    • Acts as a powerful antioxidant, protecting mitochondria from oxidative damage.
    • Supports cellular energy production by aiding in the conversion of glucose into ATP.
  • References:
    • Shay, K. P., Moreau, R. F., Smith, E. J., Smith, A. R., & Hagen, T. M. (2009). Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochimica et Biophysica Acta (BBA)-General Subjects, 1790(10), 1149-1160.
    • Zhang, Y. J., Yang, S. H., Xie, L., Yang, Y. H., & Xie, X. L. (2011). Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1, and Nrf2 via the SIRT1/LKB1/AMPK pathway. Journal of Nutritional Biochemistry, 22(10), 1008-1018.

Group IV. Amino acids: Dry Extract Thistle Mushroom (Pleurotus eryngii (DC: Fr.) Quél., Fruiting body, ratio 4:1) – for its ergotine in content:

  • Features:
    • Contains ergotinein, a bioactive compound found in thistle mushrooms.
  • Benefícios:
    • Supports mitochondrial health by providing ergotine in, which has antioxidant properties.
    • May protect mitochondria from oxidative stress and contribute to their function.
  • References:
    • Lee, S. B., Kim, M. H., & Lee, H. S. (2014). Ergothioneine accumulation in the mycelia of the culinary-medicinal king oyster mushroom, Pleurotus eryngii (higher Basidiomycetes), during spawn and fruiting body development. International Journal of Medicinal Mushrooms, 16(1), 29-37.
    • Gonçalves, R. V., Novaes, R. D., & Gonçalves, D. V. (2016). The role of ergothioneine on cognitive function in aged rats exposed to chronic mild stress. Nutritional Neuroscience, 19(1), 32-39.

Group V. Energy transfer and membrane integrity:

Phosphatidylserine 50% Powder (from Soy Lecithin), 30 mg:

  • Features:
    • Contains phosphatidylserine, a phospholipid important for cell membrane structure.
  • Benefícios:
    • Supports membrane integrity, including mitochondrial membranes, aiding in overall cell health.
    • May enhance energy transfer processes within the cell.
  • References:
    • Glade, M. J., & Smith, K. (2015). Phosphatidylserine and the human brain. Nutrition, 31(6), 781-786.
    • Monteleone, P., Beinat, L., Tanzillo, C., Maj, M., & Kemali, D. (1990). Effects of phosphatidylserine on the neuroendocrine response to physical stress in humans. Neuroendocrinology, 52(3), 243-248.

Dry Extract Thistle Mushroom (Pleurotus eryngii (DC: Fr.) Quél., Fruiting body, ratio 4:1):

  • Features:
    • Derived from the fruiting body of thistle mushroom.
  • Benefícios:
    • May contain bioactive compounds that support mitochondrial health and function.
    • May have antioxidant properties, protecting mitochondria from oxidative stress.
  • References:
    • Lee, S. B., Kim, M. H., & Lee, H. S. (2014). Ergothioneine accumulation in the mycelia of the culinary-medicinal king oyster mushroom, Pleurotus eryngii (higher Basidiomycetes), during spawn and fruiting body development. International Journal of Medicinal Mushrooms, 16(1), 29-37.
    • Gonçalves, R. V., Novaes, R. D., & Gonçalves, D. V. (2016). The role of ergothioneine on cognitive function in aged rats exposed to chronic mild stress. Nutritional Neuroscience, 19(1), 32-39.

Group VI. Transport of fatty acids necessary for the activation of aerobic metabolism at the mitochondrial level:

Acetyl-L-carnitine HCl, 120 mg:

  • Features:
    • Acetyl-L-carnitine is an acetylated form of the amino acid carnitine.
  • Benefícios:
    • Facilitates the transport of fatty acids into mitochondria for energy production.
    • Supports aerobic metabolism and overall mitochondrial function.
  • References:
    • Pettigrew, J. W., Levine, J., McClure, R. J., & Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer’s disease and geriatric depression. (2000). Molecular Psychiatry, 5(6), 616-632.
    • Sahlin, K. (2011). Boosting fat burning with carnitine: An old friend comes out from the shadow. Journal of Physiology, 589(7), 1509.

Group VII. Activation of critical enzymes in the protection of mitochondria and mitochondrial electron transport:

Ferrous Gluconate (12.52% iron), 8 mg – due to its catalase and peroxidase content:

  • Features:
    • Contains iron in the form of ferrous gluconate.
    • May contain enzymes such as catalase and peroxidase.
  • Benefícios:
    • Iron is essential for the function of enzymes involved in the protection of mitochondria.
    • Enzymes like catalase and peroxidase can help neutralize harmful reactive oxygen species in mitochondria.
  • References:
    • Halliwell, B., & Gutteridge, J. M. (1984). Oxygen toxicity, oxygen radicals, transition metals, and disease. Biochemical Journal, 219(1), 1-14.
    • Jomova, K., & Valko, M. (2011). Advances in metal-induced oxidative stress and human disease. Toxicology, 283(2-3), 65-87.

Veja o que nossos clientes existentes têm a dizer sobre nós

MEDICAL DISCLAIMER

Todos os nossos produtos são fabricados em laboratórios certificados pela FDA compatíveis com GMP na Alemanha, Suíça, EUA, Índia e Espanha. Eles são apropriadamente registrados com a FDA como suplementos dietéticos, atenuações homeopáticas ou ervas ayurvédicas. O máximo cuidado é tomado para garantir qualidade e pureza ótimas. A Biogetica é um site visitado em todo o mundo. Alguns países consideram que Ayurveda, MTC, Suplementos, Bioenergética e Homeopatia são medicamentos, enquanto outros não. Para cumprir com várias normas do FDA de numerosas nações, dizemos:

Ayurveda & Homeopathy may or may not qualify as medicine in your home jurisdiction. The complementary advice of our practitioners who are considered Homeopathic and Ayurvedic Doctors in some jurisdictions does not replace the medical advice given by your primary care physician. Biogetica’s Homeopathic products may be used for treatment of self limiting over the counter ailments in USA, India & Europe that support Homeopathy for OTC use. Biogetica’s Herbal remedies from the Ayurvedic, Chinese and other traditions may only be used to balance the 5 elements and rejuvenate organ systems in countries where Herbs, Ayurveda and TCM are not considered medicine. Biogetica’s ground breaking supplements may only be used to support the ideal structure and function of the various systems in the Human Body.

As informações fornecidas neste site não foram avaliadas pela Food and Drug Administration. Nossos produtos não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença.

* This peer reviewed and published research has most probably not been studied or approved by the FDA in your country as a treatment or cure. Hence no disease claims can be made and you are welcome to take the natural ingredients for (immunity, lung health, cardiovascular health, etc). Homeopathy is medicine in USA but only for OTC issues. Ayurveda is medicine only in India and TCM is medicine only in China. Switzerland supports insurance payments for Homeopathy.

De acordo com a Declaração da Política de Execução da FTC sobre reivindicações de marketing para medicamentos homeopáticos OTC, qualquer pessoa que venda homeopatia deve declarar.

Não há provas científicas suficientes de que a homeopatia funciona, e

The product’s claims are based only on theories of homeopathy from the 1700s that are not accepted by most modern medical experts.

** Nossos remédios foram tradicionalmente usados ​​em Ayurveda e Homeopatia há séculos. Cada remédio tem uma quantidade variável de pesquisas modernas por trás disso. Nós, ao cumprir a lei, não reivindicamos uma cura milagrosa ou resultados permanentes. Os resultados individuais podem variar de indivíduo para indivíduo.

*** Experimente os nossos produtos agora! Nossa Garantia de devolução de dinheiro incondicional 100% é válida para 90 dias.

† All Homeopathic products are made in accordance with the Homeopathic Pharmacopoeia of the United States, a document which has been published for over 100 years and which is recognized as an “official compendium” by Sections 501(b) and 502(e)(3) of the Federal Food, Drug, and Cosmetic Act, 21 U.S.C. 351(b) and 352(e)(3) (“FD&C Act”).” These indications are based solely on traditional homeopathic use. They have not been evaluated by the Food & Drug Administration.

†† These testimonials are unsolicited and unedited except for the name of the sender. They contain the senders’ initials or first name only for purposes of privacy. These are actual emails from many we were able to help over the years. Testimonials represent a cross section of the range of outcomes that appear to be typical with these products. Your results may vary. We do however stand by our products and will refund you completely if our products don’t meet your expectations.

What we do is simply point you and your Doctors to independent research from all sources that we know of, on the ingredients or entire formulation of our natural products, which are Herbal, Ayurvedic, Bioenergetic, Homeopathic and Complementary in nature. We invite you to read these studies on our clinical trials page or on scholar.google.com. Results may vary from person to person as is depicted in the wide range of results seen in the clinical trials.

 

 

0
0
Your Cart
Your cart is empty
Apply Coupon

Use coupon code "ready" for 10% off today!

FrançaisDeutschPortuguêsEspañolрусскийमानक हिन्दीEN